1. What’s rosuvastatin

Rosuvastatin belongs to a gaggle of medicines known as statins. It is used to decrease ldl cholesterol when you’ve got been identified with excessive ldl cholesterol. It is also taken to stop coronary heart and blood vessel illness, coronary heart assaults and strokes.

Your physician might also prescribe rosuvastatin when you’ve got diabetes, kidney illness, or a household historical past of rheumatoid arthritis or coronary heart illness. Rosuvastatin is accessible on prescription as tablets.

2. Key info

  • It is regular to take rosuvastatin as soon as a day.
  • Communicate to a health care provider right away if you happen to expertise any unexplained muscle aches and pains, tenderness or weak point.
  • Hold taking rosuvastatin even if you happen to really feel effectively, as you may nonetheless be getting the advantages. Most individuals with excessive ldl cholesterol shouldn’t have any signs.
  • Don’t take rosuvastatin if you happen to’re pregnant, making an attempt to get pregnant or breastfeeding.
  • Rosuvastatin can also be known as by the model title Cresto.

3. Who can and might’t take rosuvastatin

Rosuvastatin will be taken by adults and kids over the age of 6 years.

Rosuvastatin will not be appropriate for some individuals. Inform your physician if you happen to:

  • have had an allergic response to rosuvastatin or another medicines prior to now
  • have liver or kidney issues
  • are attempting to get pregnant, assume you is perhaps pregnant, are already pregnant or are breastfeeding
  • have extreme lung illness
  • take a medication known as ciclosporin
  • or an in depth relative has or have had a muscle dysfunction (together with fibromyalgia)

Rosuvastatin additionally comes as the next 40mg dose for adults. It isn’t appropriate for some individuals. Inform your physician if you happen to additionally:

  • have an underactive thyroid
  • have had issues along with your muscle tissues when taking a statin or one other ldl cholesterol reducing medication prior to now
  • frequently drink giant quantities of alcohol
  • are of Asian origin
  • take different medicines known as fibrates to decrease your ldl cholesterol

4. How and when to take it

It is regular to take rosuvastatin as soon as a day. You possibly can take it at any time so long as you persist with the identical time daily. Rosuvastatin won’t often upset your abdomen, so you possibly can take it with or with out meals. Swallow rosuvastatin tablets complete with a glass of water.

How a lot to take

How a lot you’re taking is determined by what you take rosuvastatin for:

  • stopping coronary heart assaults and strokes – the same old dose for adults is 20mg as soon as a day. Typically a decrease dose could also be prescribed.
  • excessive ldl cholesterol – the same old beginning dose for adults and kids is 5mg to 10mg as soon as a day. If wanted, your physician might improve your dose each 4 weeks as much as 20mg a day.

The utmost dose for kids is 20mg a day.

When you’ve got very excessive ldl cholesterol, chances are you’ll be prescribed the next dose of 40mg a day by a specialist. This dosage will not be appropriate for everybody.

Ask your physician or pharmacist for recommendation if you happen to’re not sure how a lot to take. Don’t scale back your dose with out speaking to your physician first.

What if I neglect to take it?

  • For those who neglect to take a dose, skip the missed dose and take your subsequent one the subsequent day on the regular time.
  • By no means take 2 doses on the identical time. By no means take an additional dose to make up for the forgotten one.
  • For those who neglect doses usually, it could assist to set an alarm to remind you.
  • You may additionally ask your pharmacist for recommendation on different methods that will help you bear in mind to take your medication.

What if I take an excessive amount of?

The quantity of rosuvastatin that may result in an overdose varies from individual to individual.

Pressing recommendation: Name your physician right away if you happen to take an excessive amount of rosuvastatin

If you could go to A&E, don’t drive your self – get another person to drive you or name for an ambulance. Take the rosuvastatin packet or the leaflet inside it, plus any remaining medication with you.

5. Negative effects

  • Like all medicines, rosuvastatin may cause unwanted side effects, though not everybody will get them. Negative effects usually enhance as your physique will get used to the medication.
  • One uncommon however critical facet impact is unexplained muscle aches and pains, tenderness or weak point. This may occur a couple of weeks or months after you first begin taking this medication.
  • Report any unexplained muscle aches and pains, tenderness or weak point to a health care provider right away.
  • Speak to your physician or a pharmacist if unwanted side effects are bothering you. They might suggest making an attempt another statin.

Widespread unwanted side effects

These unwanted side effects occur in additional than 1 in 100 individuals. Hold taking the medication, however inform your physician or pharmacist if these unwanted side effects hassle you or don’t go away:

  • feeling sick
  • complications
  • abdomen ache
  • feeling weak or dizzy
  • constipation
  • protein in your pee (if you happen to’re taking the upper 40mg dose) – your physician will test for this as there are not any signs for this facet impact

Critical unwanted side effects

Critical unwanted side effects are uncommon and occur in lower than 1 in 1,000 individuals. Cease taking rosuvastatin and name a health care provider if you happen to get:

  • muscle ache, tenderness, weak point or cramps – these will be indicators of muscle breakdown and kidney injury
  • yellow pores and skin or the whites of your eyes flip yellow – these will be indicators of liver issues
  • extreme abdomen ache – this could be a signal of pancreas issues
  • a cough, shortness of breath and weight reduction – these will be indicators of lung illness

Lower than 1 in 10,000 individuals might expertise reminiscence loss. For those who expertise issues along with your reminiscence, communicate to your physician, as it could be unrelated to rosuvastatin. Don’t cease taking the medication with out speaking to your physician first.

Critical allergic response

In uncommon circumstances, it is potential to have a critical allergic response (anaphylaxis) to rosuvastatin.

Speedy motion required: Name 999 or go to A&E if:

  • you get a pores and skin rash that will embrace itchy, pink, swollen, blistered or peeling pores and skin
  • you are wheezing
  • you get tightness within the chest or throat
  • you might have hassle respiration or speaking
  • your mouth, face, lips, tongue or throat begin swelling

You may be having a critical allergic response and might have speedy remedy in hospital.

These aren’t all of the unwanted side effects of rosuvastatin.

6. How to deal with unwanted side effects

What to do What’s:

  • feeling sick – persist with easy meals and don’t eat wealthy or spicy meals. It’d assist to take your rosuvastatin after a meal or snack. Contact your physician in case your signs proceed for quite a lot of days or worsen.
  • complications – ensure you relaxation and drink loads of fluids. Don’t drink an excessive amount of alcohol. Ask your pharmacist to suggest a painkiller. Speak to your physician in the event that they last more than per week or are extreme.
  • abdomen ache – attempt to relaxation and chill out. It will probably assist to eat and drink slowly and have smaller and extra frequent meals. Placing a warmth pad or coated sizzling water bottle in your tummy might also assist. For those who’re in a number of ache, communicate to your pharmacist or physician.
  • feeling weak or dizzy – if rosuvastatin makes you are feeling dizzy or weak, cease what you are doing and sit or lie down till you are feeling higher. Don’t drive or use instruments or equipment if you happen to’re feeling drained. Don’t drink alcohol as it will make you are feeling worse.
  • constipation – eat extra high-fibre meals, corresponding to recent fruit, greens and cereals, and drink loads of water. Attempt to train extra frequently, for instance, by going for a each day stroll or run. If this doesn’t assist, speak to your pharmacist or physician. Watch this brief video What’s learn how to deal with constipation.
  • protein in your pee – this often returns to regular by itself with out you having to cease taking rosuvastatin. Your physician might need to monitor you to test this occurs.

7. Being pregnant and breastfeeding

Rosuvastatin will not be really helpful throughout being pregnant or breastfeeding, as there isn’t any agency proof it is protected.

If you wish to get pregnant, communicate to your physician. It is best to cease taking rosuvastatin a minimum of 3 months earlier than you begin making an attempt for a child.

For those who grow to be pregnant whereas taking rosuvastatin, cease taking the medication and inform your physician.

Rosuvastatin and breastfeeding

It isn’t identified if rosuvastatin passes into breast milk, however it could trigger issues in your child. Communicate to your physician What’s what’s finest for you and your child when you’re breastfeeding. It might be potential to delay beginning or restarting rosuvastatin till you might have stopped breastfeeding utterly.

Non-urgent recommendation: Inform your physician if you happen to’re:

  • making an attempt to get pregnant
  • pregnant
  • breastfeeding

8. Cautions with different medicines

Some medicines and rosuvastatin can intrude with one another and improve the possibilities of you having unwanted side effects.

Inform your physician if you happen to’re taking:

  • antibiotics, corresponding to erythromycin
  • some antiviral medicines used to deal with infections, corresponding to HIV and hepatitis
  • medication for indigestion, corresponding to Gaviscon
  • blood-thinning medicines, corresponding to clopidogrel and warfarin
  • ciclosporin, used to deal with psoriasis and rheumatoid arthritis
  • contraceptive capsules and hormone alternative remedy
  • different drugs used to decrease ldl cholesterol

For those who’re taking rosuvastatin and have to take one in all these medicines, your physician might decrease your dose or prescribe a unique statin.

If you could take an antibiotic, your physician would possibly suggest you cease taking rosuvastatin for some time. These aren’t all of the medicines that may intrude with rosuvastatin. For a full listing, see the leaflet inside your medication packet or test along with your pharmacist.

Mixing rosuvastatin with natural cures and dietary supplements

There’s little or no info What’s taking natural cures and dietary supplements when you use rosuvastatin.

Necessary

For security, inform your physician and pharmacist if you happen to’re taking another medicines, together with natural cures, nutritional vitamins or dietary supplements.

9. Widespread questions

  1. How does rosuvastatin work?

    Rosuvastatin acts on the liver to cease it making ldl cholesterol. This lowers your ldl cholesterol degree. For the primary 12 months on this medication, you may be provided some routine exams to verify your liver is working usually.

  2. How lengthy does rosuvastatin take to work?

    Rosuvastatin begins to work inside per week to scale back ldl cholesterol, however it could actually take as much as a month to attain its full impact.

  3. How lengthy will I take rosuvastatin for?

    Normally you may take rosuvastatin for all times. The advantages will solely proceed for so long as you're taking it. For those who cease taking rosuvastatin with out beginning a unique remedy, your ldl cholesterol degree might rise once more.

  4. Is it protected to take rosuvastatin for a very long time?

    Rosuvastatin is protected to take for a very long time, even a few years. In actual fact, it really works finest whenever you take it for a very long time.

  5. Are statins protected?

    You might have learn detrimental tales What's statins, however, they're regarded as very protected, efficient medicines. Statins are thought to have only a few unwanted side effects. Typically the unwanted side effects that individuals report aren't associated to their medication. However if you happen to involved What's the security of statins, speak to your physician.

  6. What's going to occur if I cease taking it?

    Chances are you'll need to cease rosuvastatin if you happen to assume you are having unwanted side effects. Speak to your physician first to see if it truly is a facet impact of rosuvastatin or an unrelated downside. Your physician might resolve to decrease your dose or change your medication.

    You'll not get any withdrawal signs. However stopping rosuvastatin might trigger your ldl cholesterol to rise. This will increase your threat of coronary heart assaults and strokes. If you wish to cease taking your medication, it is vital to search out one other option to decrease your ldl cholesterol.

  7. Is rosuvastatin addictive?

    No, there isn't any proof that rosuvastatin is addictive.nYou'll not get any withdrawal signs whenever you cease taking it.

  8. How does it evaluate with different statins?

    There are a number of different statin medicines, together with:
    -atorvastatin
    -fluvastatin
    -pravastatin
    -simvastatin

    Statins all work in the identical method, however they differ in how effectively they decrease ldl cholesterol. When used at the next dose, rosuvastatin and atorvastatin produce a much bigger discount in ldl cholesterol than the opposite statins.

    When you've got a facet impact with one statin, it could not occur with one other. Some medicines don't combine effectively with one statin, however are OK to take with different ones. Your physician will discover the proper statin and dose for you, relying in your medical historical past, ldl cholesterol degree and the opposite medicines you're taking.

  9. Will taking rosuvastatin improve my threat of diabetes?

    For those who're at excessive threat of growing kind 2 diabetes, taking statins might barely improve this threat. It's because statins can elevate your blood sugar a bit of. Communicate to your physician, who will be capable of clarify how the advantages of taking statins are more likely to outweigh this small elevated threat.

    If you have already got kind 2 diabetes, your physician might advise monitoring your blood sugar ranges extra intently for the primary few months. Inform your physician or diabetes nurse if you happen to discover it more durable to manage your blood sugar.

  10. Does it assist to take dietary supplements along with statins?

    There's some curiosity in taking CoQ10 along with statins. However there isn't any agency proof that taking CoQ10 similtaneously rosuvastatin will profit your well being. Extra analysis is required.

  11. Can I drink alcohol with it?

    Sure, you possibly can drink alcohol whereas taking rosuvastatin. However consuming a number of alcohol might imply you are extra more likely to get muscle and liver unwanted side effects. Strive to not drink greater than 14 items of alcohol per week.

    A regular glass of wine (175ml) is 2 items. A pint of lager or beer is often 2 to three items of alcohol.

  12. Is there any meals or drink I have to keep away from?

    You possibly can eat and drink usually on rosuvastatin. In contrast to with different statins, like simvastatin and atorvastatin, it is protected to drink grapefruit juice with rosuvastatin.

  13. Will it cease my contraception working?

    For girls, rosuvastatin might barely improve the hormones launched into your system from some contraceptive capsules. You may nonetheless be protected against being pregnant, however this might improve your possibilities of having unwanted side effects from contraceptive capsules. When you've got any unwanted side effects, speak to your physician or pharmacist.

  14. Will it have an effect on my fertility?

    There is no agency proof to recommend that taking rosuvastatin will scale back fertility in both males or ladies. However if you happen to're a girl and also you're making an attempt to get pregnant, speak to your physician first. This medication will not be really helpful in being pregnant.

  15. Can I drive or trip a motorbike?

    Typically rosuvastatin could make you are feeling dizzy. If this occurs to you, don't drive, cycle or use machines or instruments till you are feeling higher.

  16. Can life-style modifications assist?

    Decreasing your ldl cholesterol might imply you do not want to be prescribed a statin medication. There are life-style modifications you can also make that can assist decrease your ldl cholesterol and scale back your threat of getting a coronary heart assault or a stroke:
    -ensure you're a wholesome weight
    -eat effectively – reduce saturated fats and improve fibre, fruits, greens, wholegrains and fish
    -stop smoking
    -reduce down on alcohol
    -attempt to train daily

Associated circumstances

  • Angina
  • Heart problems
  • Coronary heart assault
  • Stroke

Helpful assets

  • Atorvastatin: boards
  • British Coronary heart Basis: charity
  • Coronary heart UK: charity
  • Statins: movies of actual tales
  • Stroke Affiliation: charity

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